These antigens are mainly administered during childhood, but may be recommended for travellers to endemic or epidemic areas in any country. Travellers who are not fully immunized against measles, mumps and rubella are at risk when visiting endemic areas or countries where vaccine coverage is suboptimal.

Considering rubella infection and its possible effects when contracted during pregnancy, women from countries with low incidence that haven´t been vaccinated should check their immune status before departure, mainly when the destination is an endemic region.

Special attention must be paid to children, adolescents and young adults travellers who haven´t been vacinated against measles. This disease is still endemic in many countries, and travel in densely populated areas may favour transmission. For infants travelling to regions where measles is endemic, a dose of vaccine (MMR or monovalent measles vaccine) may be given as early as 6 months of age (dose "zero"); subsequently should be vaccinated according to the national immunization schedule. Older children and adults who did not receive the two lifetime doses should be vaccinated.

Live vaccines, either mono/bivalent or trivalent, should not be given to women known to be pregnant or who might become pregnant within three months after vaccination.

Fernando Costa Silva, 1999 (last update: 2009)