Integrated Program for the
Eradication of Poliomyelitis in Macau

Surveillance Case Definitions

Standard definition of AFP case:

Any case of Acute Flaccid Paralysis in a child under 15 years of age, including those considered to be Guillan-Barre Syndrome;

This definition also includes any suspected case of poliomyelitis, transverse myelitis, traumatic neuritis, Pott’s disease, TB meningitis, all other forms of meningitis, osteomyelitis, hypotonia or hypokalemic paralysis.

Clinical case definition of poliomyelitis (as reported by a physician):

Acute onset of a flaccid paralysis of one or more limbs with decreased or absent tendon reflexes in the affected limbs, without other apparent cause, and without sensory or cognitive loss.

Probable case of poliomyelitis:

A case that meets the clinical case definition, without isolation of poliovirus from laboratory specimens.

Confirmed case of poliomyelitis:

A case that meets the clinical case definition and in which the patient has a neurologic deficit sixty (60) days after onset of initial symptoms, has died, or has unknown follow-up status; or

A case that meets the clinical case definition and is associated with the isolation of wild or vaccine poliovirus from a clinical / laboratory specimen.

Categories of poliomyelitis cases:

Wild virus: laboratory investigation implicates wild-type virus. This group is further sub-divided in:

indigenous: a case that cannot be proved to be imported; and

imported: a case which has its source outside Macau. A person with poliomyelitis (Macau resident or other) who has entered the territory and had onset of illness within thirty (30) days before or after entry.

Vaccine-associated: laboratory investigation implicates vaccine-type virus. This group can be further sub-divided in:

recipient: the illness began 7-30 days after receiving OPV;

contact: the patient was shown to have been in contact with a vaccinee and became ill 7-60 days after the vaccinee received OPV; and

immunocompromised: diagnosis of a concurrent medical condition associated with deficient immune function in any vaccine-associated case.

© Fernando Costa Silva, 1999